New Updates On the Perio-Diabetes Link

Earlier this year, delegates of the European Federation of Periodontology (EFP) and the International Diabetes Federation (IDF) had met in Madrid for a joint workshop on an update of the Perio-Diabetes link. I had reported on the event and some key findings, quickly posted on the EFP web page, here.

Already on and after 24 August 2017, a Consensus Report by the two organizations was prematurely published, and quickly (temporarily) withdrawn, in the EFP’s Journal of Clinical Periodontology and the IDF’s Diabetes Research and Clinical Practice. I had managed to get a print-out of the not-yet edited (and later withdrawn) draft version published on the JCP Accepted Articles page and had noticed that most of the evidence presented was derived of yet-to-be published review articles based on the workshop proceedings.

The final version of the Consensus Report (Sanz et al. 2017, Early View Articles), including guidelines for patients and health professionals dealing with patients suffering from diabetes and periodontal disease, went online this week, but still references to review papers presented on the occasion of the workshop have a 2017 assignment and are not paginated which may make it more difficult for scientists and clinicians outside periodontology or dentistry to locate the final papers.

To be clear, when it comes to keeping our medical collegues, and in particular diabetologists, interested in the very long-known link between periodontitis and metabolic diseases, proving beneficial effects of periodontal treatment on diabetic control is crucial. All was fine as long as numerous published, small-scale, mostly single-center, and often poorly executed, trials apparently showed that thorough subgingival scaling in patients with both periodontitis and diabetes led to an about 0.4% reduction of glycated hemoglobin (HbA1c), at least after three or four months. As that would in effect spare an additional antidiabetic drug, diabetologists stayed interested. Although results in a few trials indicated that the effect was not long-lasting, i.e., no longer discernable after, say, six months.

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A New Classification of Periodontal Diseases


EFP_AAP 2017

Another edition of a joint EFP/AAP workshop has just closed in Chicago, and periodontal scientists and teachers all over the world are eagerly awaiting the proceedings to be published in our core scinetific journals, the Journal of Periodontology and the Journal of Clinical Periodontology. The workshop’s agenda had been announced on the EFP website on Thursday this week.

Hallmarks of the previous Classification of Periodontal Diseases and Conditions of 1999 had included a thorough classification of gingival diseases and renaming, once more, juvenile/early-onset periodontitis as “aggressive”, and the more common “adult” form of periodontitis as “chronic”. Many scientists, in particular epidemiologists had considered the latter achievement as highly problematic. Not only that disease definitions included some laboratory tests not available to the common practitioner; progression rates were to be assessed as well. Both is utterly difficult, if impossible, in epidemiological research.

And, as assumed microbiological cause and pathogenesis of either chronic or aggressive periodontitis do not differ fundamentally, does a differentiation even make sense? What comes to one’s mind is, of course, diabetes where types I and II have different causation and can easily be differentiated despite common clinical signs and symptoms.

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Root-resective Therapy is a Predictable Treatment Option When Care is Administered at Each Phase of Therapy

The above is the conclusion of a recent retrospective evaluation of root-resected molars during a time-span of 30 years in a private practice. I would like to draw attention in particular to the last part of the sentence which is of utmost importance. I shall explain below, what I think is necessary when reporting research findings in an honest way.

When has root resection been reported first?

Root resection, or amputation, is an old story. According to common wisdom, it had been Dr. John N. Farrar from Brooklyn, NY, who had reported first on so-called “radical and heroic treatment” of alveolar abscesses by amputation of roots of teeth [1], “in order to enable nature to have a better chance for cure.” Dr. Farrar correctly stated that, “if an entire tooth should be extracted from a diseased socket, the treatment might be termed highly radical.” He considered that such a treatment might not only unwise and unnecessary but “absolutely wrong and unscientific [sic].”

It is amazing that, some 130 years ago, reporting couple of cases was considered “science”. The times they are a changin’. Maybe in 100 years our current approach to what is still regarded scholarship and science will be ridiculed as well.

What can be achieved

Root resection or hemisection of furcation-involved molars are still common treatment options based on more rigorous research in the past 45 years. There may be also other indications, endodontic and iatrogenic. Implant dentistry is of course an interesting alternative, and a not so recent case series of patients attending a single private practice by  Fugazzotto (2001) from Milton, MA, had shown comparable results regarding successful treatment of either root resection of molars (n=701) or placing implants in molar locations (n=1472) after 15 and more years and 13 years, respectively. Indeed remarkable results, namely success rates of 96.8% for root resected molars and 97% for implants.

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Periodontal Myths and Mysteries Series (VIII) – Disabling Periodontitis

Shortly before recent updates of the Global Burden of Disease (GBD) studies (supported by the Bill & Melinda Gates Foundation) sparked considerable attention in the news, dubious metrics  like disability-adjusted life years (DALY) and years lived with disability (YLD) had been calculated for a number of oral diseases and conditions such as (severe) periodontitis. These metrics are basically derived from estimates of incidence (and, recently also, prevalence) of the disease, and a disability weighing factor; but interpretation must be regarded spurious. One may intuitively ask the important question, cui bono?

In its recent update on the global burden of oral diseases, Kassebaum et al. (2017) claimed 538 million cases of severe periodontitis worldwide in 2015, 231 million more than estimated for 1990. Disability-adjusted life years (DALY) for severe periodontitis were calculated at 3.518 million. In a recent white paper by Tonetti et al. (2017), this latter figure was emphasized, “3.5 million years lived with disability.” These authors further their arguments about the “Impact of global burden of periodontal diseases on health, nutrition and wellbeing of mankind” by adding estimates provided by Listl et al. (2015) on the global cost of lost productivity from severe periodontitis alone (54 billion USD/yr). Productivity loss values 1 DALY as 1 yr of per capita gross domestic product.

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Professor Dieter E. Lange †


Photo: FZ, under fair use

Shortly after his 84th birthday, Professor Dr. med. dent. Dr. h.c. Dieter E. Lange,  former director of Germany’s once largest, independent department of Periodontology at Westfälische-Wilhelms-Universität Münster, passed on 12 September.

At a time when Periodontology in Germany was largely non-existent in the dental curriculum and consequently in dental practice, Professor Lange started, in 1978 after having been appointed in Münster, his crusade for prevention and treatment of periodontal diseases. He was the one who managed to get soon afterwards approval, by the Westphalian-Lippe dental association, of Germany’s first and still only postgraduate education program in Periodontology. I had had my education in Perio in Marburg, Hesse, but if I wanted to get a respective official certificate I had eventually to move to Münster, what I actually did in 1987.

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